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AG-18 
2-​[(3,​4-​dihydroxyphenyl)methylene]-​propanedinitrile
(CAS 118409-57-7)
Description:

Protein tyrosine kinase (PTK) inhibitors are potential antiproliferative agents for diseases caused by the hyperactivity of PTKs. Tyrphostins are a class of antiproliferative compounds which act as protein tryrosine kinase blockers. PTK inhibitors which preferentially inhibit the epidermal growth factor (EGF) receptor kinase block EGF-dependent cell proliferation. AG-18 is an inhibitor of epidermal growth factor (EGF) receptor kinase with an IC50 value of 35 µM in the human epidermoid carcinoma cell line A431.

 

Product No. KT00050 
Product Name AG-18 
Synonyms RG-50858,TX 825,Tyrphostin 23,Tyrphostin AG-18,RG-50810
Formal Name 2-​[(3,​4-​dihydroxyphenyl)methylene]-​propanedinitrile
CAS Number 118409-57-7
Molecular Formula C10H6N2O2
Formula Weight 186.1
Formulation A crystalline solid
Purity 98%min
Stability 1 year
Storage -20°C
Shipping USD45 for Europe and USA. No shipping charge once amount reach USD500.
Quality Control HNMR,CNMR,LCMS,HPLC,IR,etc.
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