| AG-18 |
| 2-[(3,4-dihydroxyphenyl)methylene]-propanedinitrile |
| (CAS 118409-57-7) |
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| Description： |
Protein tyrosine kinase (PTK) inhibitors are potential antiproliferative agents for diseases caused by the hyperactivity of PTKs. Tyrphostins are a class of antiproliferative compounds which act as protein tryrosine kinase blockers. PTK inhibitors which preferentially inhibit the epidermal growth factor (EGF) receptor kinase block EGF-dependent cell proliferation. AG-18 is an inhibitor of epidermal growth factor (EGF) receptor kinase with an IC50 value of 35 µM in the human epidermoid carcinoma cell line A431. |
| Product No. |
KT00050 |
| Product Name |
AG-18 |
| Synonyms |
RG-50858,TX 825,Tyrphostin 23,Tyrphostin AG-18,RG-50810 |
| Formal Name |
2-[(3,4-dihydroxyphenyl)methylene]-propanedinitrile |
| CAS Number |
118409-57-7 |
| Molecular Formula |
C10H6N2O2 |
| Formula Weight |
186.1 |
| Formulation |
A crystalline solid |
| Purity |
98%min |
| Stability |
1 year |
| Storage |
-20°C |
| Shipping |
USD45 for Europe and USA. No shipping charge once amount reach USD500. |
| Quality Control |
HNMR,CNMR,LCMS,HPLC,IR,etc. |
| Price & Availability |
In Stock. Price Negotiated. |
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