AG-17 |
2-[[3,5-bis(1,1-dimethylethyl)-4-hydroxyphenyl]methylene]-propanedinitrile |
(CAS 10537-47-0) |
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Description: |
Protein tyrosine kinase (PTK) inhibitors are potential antiproliferative agents for diseases caused by the hyperactivity of protein tyrosine kinases. Tyrphostins are a class of antiproliferative compounds which act as protein tryrosine kinase blockers. PTK inhibitors which preferentially inhibit the epidermal growth factor (EGF) receptor kinase block EGF-dependent cell proliferation. AG-17 is an inhibitor of epidermal growth factor (EGF) receptor kinase with an IC50 value of 460 µM in the human epidermoid carcinoma cell line A431. |
Product No. |
KT00059 |
Product Name |
AG-17 |
Synonyms |
Tyrphostin 9,Malonoben,Tyrphostin AG-17,SF 6847,GCP 5126,RG-50872,NSC 242557 |
Formal Name |
2-[[3,5-bis(1,1-dimethylethyl)-4-hydroxyphenyl]methylene]-propanedinitrile |
CAS Number |
10537-47-0 |
Molecular Formula |
C18H22N2O |
Formula Weight |
282.4 |
Formulation |
A crystalline solid |
Purity |
98%min |
Stability |
1 year |
Storage |
-20°C |
Shipping |
USD45 for Europe and USA. No shipping charge once amount reach USD500. |
Quality Control |
HNMR,CNMR,LCMS,HPLC,IR,etc. |
Price & Availability |
In Stock. Price Negotiated. |
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