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AG-17 
2-​[[3,​5-​bis(1,​1-​dimethylethyl)-​4-​hydroxyphenyl]methylene]-​propanedinitrile
(CAS 10537-47-0)
Description:

Protein tyrosine kinase (PTK) inhibitors are potential antiproliferative agents for diseases caused by the hyperactivity of protein tyrosine kinases. Tyrphostins are a class of antiproliferative compounds which act as protein tryrosine kinase blockers. PTK inhibitors which preferentially inhibit the epidermal growth factor (EGF) receptor kinase block EGF-dependent cell proliferation. AG-17 is an inhibitor of epidermal growth factor (EGF) receptor kinase with an IC50 value of 460 µM in the human epidermoid carcinoma cell line A431.

 

Product No. KT00059 
Product Name AG-17 
Synonyms Tyrphostin 9,Malonoben,Tyrphostin AG-17,SF 6847,GCP 5126,RG-50872,NSC 242557
Formal Name 2-​[[3,​5-​bis(1,​1-​dimethylethyl)-​4-​hydroxyphenyl]methylene]-​propanedinitrile
CAS Number 10537-47-0
Molecular Formula C18H22N2O
Formula Weight 282.4
Formulation A crystalline solid
Purity 98%min
Stability 1 year
Storage -20°C
Shipping USD45 for Europe and USA. No shipping charge once amount reach USD500.
Quality Control HNMR,CNMR,LCMS,HPLC,IR,etc.
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