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AG-183 
2-​amino-​4-​(3,​4,​5-​trihydroxyphenyl)-​1,​3-​butadiene-​1,​1,​3-​tricarbonitrile
(CAS 122520-90-5)
Description:

Protein tyrosine kinase (PTK) inhibitors are potential antiproliferative agents for diseases caused by the hyperactivity of PTKs. Tyrphostins are a class of antiproliferative compounds which act as PTK blockers. PTK inhibitors which preferentially inhibit the epidermal growth factor (EGF) receptor kinase block EGF-dependent cell proliferation. AG-183 is an inhibitor of epidermal growth factor (EGF) receptor kinase with an IC50 value of 0.8 µM in the human epidermoid carcinoma cell line A431.

 

Product No. KT00052 
Product Name AG-183 
Synonyms Tyrphostin 51
Formal Name 2-​amino-​4-​(3,​4,​5-​trihydroxyphenyl)-​1,​3-​butadiene-​1,​1,​3-​tricarbonitrile
CAS Number 122520-90-5
Molecular Formula C13H8N4O3
Formula Weight 268.2
Formulation A crystalline solid
Purity 98%min
Stability 1 year
Storage -20°C
Shipping USD45 for Europe and USA. No shipping charge once amount reach USD500.
Quality Control HNMR,CNMR,LCMS,HPLC,IR,etc.
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