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AG-82 
2-​[(3,​4,​5-​trihydroxyphenyl)methylene]-​propanedinitrile
(CAS 118409-58-8)
Description:

rotein tyrosine kinase (PTK) inhibitors are potential antiproliferative agents for diseases caused by the hyperactivity of PTKs. Tyrphostins are a class of antiproliferative compounds that act as PTK blockers. PTK inhibitors which preferentially inhibit the epidermal growth factor (EGF) receptor kinase block EGF-dependent cell proliferation. AG-82 is an inhibitor of epidermal growth factor receptor kinase with an IC50 value of 3 µM in the human epidermoid carcinoma cell line A431.

 

Product No. KT00053 
Product Name AG-82 
Synonyms Tyrphostin 25,RG-50875,NSC 676484,Tyrphostin AG-82
Formal Name 2-​[(3,​4,​5-​trihydroxyphenyl)methylene]-​propanedinitrile
CAS Number 118409-58-8
Molecular Formula C10H6N2O3
Formula Weight 202.2
Formulation A crystalline solid
Purity 98%min
Stability 1 year
Storage -20°C
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Quality Control HNMR,CNMR,LCMS,HPLC,IR,etc.
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