SAHA |
N1-hydroxy-N8-phenyl-octanediamide |
(CAS 149647-78-9) |
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Description: |
SAHA is an HDAC inhibitor with IC50 of ~10 nM.
SAHA is an histone deacetylase (HDAC) inhibitor that binds directly to the catalytic site of the enzyme thereby blocking substrate access. It inhibits class I and class II HDACs at around 50 nM and arrests cell growth in a wide variety of transformed cells in culture at 2.5-5.0 µM.SAHA is currently in advanced clinical trials for the treatment of cancer. |
Product No. |
KT00789 |
Product Name |
SAHA |
Synonyms |
MK0683;Vorinostat;Suberoylanilide hydroxamic acid |
Formal Name |
N1-hydroxy-N8-phenyl-octanediamide |
CAS Number |
149647-78-9 |
Molecular Formula |
C14H20N2O3 |
Formula Weight |
264.32 |
Formulation |
A crystalline solid |
Purity |
98%min |
Stability |
2 years |
Storage |
-20°C |
Shipping |
USD45 for Europe and USA. No shipping charge once amount reach USD500 |
Quality Control |
HNMR,CNMR,LCMS,HPLC,IR,etc. |
Price & Availability |
In Stock. Price Negotiated. |
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