Nexturastat A |
4-((1-BUTYL-3-PHENYLUREIDO)METHYL)-N-HYDROXYBENZAMIDE |
(CAS 1403783-31-2) |
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Description: |
Nexturastat A is a potent and selective HDAC6 inhibitor with IC50 of 5 nM; no inhibition on other HDAC forms.
exturastat A displayed low micromolar activity compared to the low nanomolar activity against HDAC6. Moreover, it also demonstrated high levels of selective inhibition against members of the related Class 2 HDAC isozymes reaching >1000-fold selective in some cases. Compared to the pan-selective HDACI LBH589, Nexturastat A is approximately 100-fold less potent in inducing murine B16 melanoma cell death.
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Product No. |
KT01031 |
Product Name |
Nexturastat A |
Synonyms |
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Formal Name |
4-((1-BUTYL-3-PHENYLUREIDO)METHYL)-N-HYDROXYBENZAMIDE |
CAS Number |
1403783-31-2 |
Molecular Formula |
C19H23N3O3 |
Formula Weight |
341.4 |
Formulation |
A crystalline solid |
Purity |
98%min |
Stability |
2 years |
Storage |
-20°C |
Shipping |
USD45 for Europe and USA. No shipping charge once amount reach USD500 |
Quality Control |
HNMR,CNMR,LCMS,HPLC,IR,etc. |
Price & Availability |
In Stock. Price Negotiated. |
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