| JNJ-40411813 |
| 1-butyl-3-chloro-4-(4-phenylpiperidin-1-yl)pyridin-2(1H)-one |
| (CAS 1127498-03-6) |
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| Description： |
JNJ-40411813 is a novel positive allosteric modulator of the metabotropic Glutamate 2 receptor (mGlu2R) with EC50 of 147 nM.
JNJ-40411813 displayed an optimal interplay between potency, selectivity, favorable ADMET/PK and cardiovascular safety profile, and central EEG activity. JNJ-40411813 has been investigated in the clinic for schizophrenia and anxious depression disorders. |
| Product No. |
KT01042 |
| Product Name |
JNJ-40411813 |
| Synonyms |
JNJ40411813; JNJ 40411813 |
| Formal Name |
1-butyl-3-chloro-4-(4-phenylpiperidin-1-yl)pyridin-2(1H)-one |
| CAS Number |
1127498-03-6 |
| Molecular Formula |
C20H25ClN2O |
| Formula Weight |
344.88 |
| Formulation |
A crystalline solid |
| Purity |
98%min |
| Stability |
2 years |
| Storage |
-20°C |
| Shipping |
USD45 for Europe and USA. No shipping charge once amount reach USD500 |
| Quality Control |
HNMR,CNMR,LCMS,HPLC,IR,etc. |
| Price & Availability |
In Stock. Price Negotiated. |
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