| Idarubicin hydrochloride |
| (7S,9S)-9-acetyl-7-[(3-amino-2,3,6-trideoxy-α-L-lyxo-hexopyranosyl)oxy]-7,8,9,10-tetrahydro-6,9,11-trihydroxy-5,12-naphthacenedione, monohydrochloride |
| (CAS 57852-57-0) |
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| Description： |
Idarubicin is a 4-demethoxy analog of the leukemia therapeutic daunorubicin (Item No. 14159). Both are anthracycline antibiotics which intercalate in DNA and inhibit topoisomerase II, resulting in cancer cell cytotoxicity at low concentrations (IC50 = 20-120 nM for idarubicin). Idarubicin is effective in combination therapy for the treatment of different types of leukemia.
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| Product No. |
KT20021 |
| Product Name |
Idarubicin hydrochloride |
| Synonyms |
4-Demethoxydaunorubicin hydrochloride;4-DMD; NSC 256439 |
| Formal Name |
(7S,9S)-9-acetyl-7-[(3-amino-2,3,6-trideoxy-α-L-lyxo-hexopyranosyl)oxy]-7,8,9,10-tetrahydro-6,9,11-trihydroxy-5,12-naphthacenedione, monohydrochloride |
| CAS Number |
57852-57-0 |
| Molecular Formula |
C26H27NO9 • HCl |
| Formula Weight |
534.0 |
| Formulation |
A crystalline solid |
| Purity |
98%min |
| Stability |
1 year |
| Storage |
-20°C |
| Shipping |
USD45 for Europe and USA. No shipping charge once amount reach USD500. |
| Quality Control |
HNMR,CNMR,LCMS,HPLC,IR,etc. |
| Price & Availability |
In Stock. Price Negotiated. |
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