| GNF5837 |
|
| (CAS 1033769-28-6) |
 |
| Description： |
Biological Activity Potent pan-Trk inhibitor. Displays antiproliferative effects in cellular Ba/F3 assays (IC50 values are 7, 9 and 11 nM for cells containing the fusion proteins Tel-TrkC, Tel-TrkB and Tel-TrkA, respectively). Exhibits selectivity for Trk receptors over a range of kinases, with some activity at PDGFR and c-Kit (IC50 values are 0.87 and 0.91M respectively). Orally bioavailable.
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| Product No. |
KT00381 |
| Product Name |
GNF5837 |
| Synonyms |
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| Formal Name |
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| CAS Number |
1033769-28-6 |
| Molecular Formula |
C28H21F4N5O2 |
| Formula Weight |
535.49 |
| Formulation |
A crystalline solid |
| Purity |
98%min |
| Stability |
2 years |
| Storage |
-20°C |
| Shipping |
USD45 for Europe and USA. No shipping charge once amount reach USD500 |
| Quality Control |
HNMR,CNMR,LCMS,HPLC,IR,etc. |
| Price & Availability |
In Stock. Price Negotiated. |
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