| GDC-0879 |
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| (CAS 905281-76-7) |
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| Description： |
GDC-0879 is a highly selective, novel potent, orally bioavailable B-Raf inhibitor in various in vitro and cell-based assays with an IC50 estimate of 0.13 nM against purified B-Raf V600E enzyme and a cellular pERK IC50 of 63 nM in the MALME-3M cell line .For this compound, subnanomolar enzyme potency translated into very effective reduction of cellular viability of BRAF-mutant Malme3M cells (EC50 values were 0.75 µmol/L for GDC-0879).
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| Product No. |
KT00369 |
| Product Name |
GDC-0879 |
| Synonyms |
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| Formal Name |
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| CAS Number |
905281-76-7 |
| Molecular Formula |
C19H18N4O2 |
| Formula Weight |
334.37 |
| Formulation |
A crystalline solid |
| Purity |
98%min |
| Stability |
2 years |
| Storage |
-20°C |
| Shipping |
USD45 for Europe and USA. No shipping charge once amount reach USD500 |
| Quality Control |
HNMR,CNMR,LCMS,HPLC,IR,etc. |
| Price & Availability |
In Stock. Price Negotiated. |
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