| U-0126 |
| 2,3-Bis[amino[(2-aminophenyl)thio]methylene]butanedinitrile |
| (CAS 109511-58-2) |
 |
| Description： |
U-0126 is a selective MAP Kinase Kinase (MKK, MEK) inhibitor with IC50 values of 72 nM and 58 nM for MEK1 and MEK2, respectively.It shows little to no inhibition against a number of other kinases including PKC, Ab1, Raf, MEKK, ERK, JNK, MKK-3, MKK-4, MKK-6, Cdk2, and Cdk4. U-0126 inhibition of MEK is noncompetitive with respect adenosine triphosphate (ATP) and its phosphorylation target ERK, which may partially explain its selectivity profile against other kinases.
|
| Product No. |
KT00930 |
| Product Name |
U-0126 |
| Synonyms |
U0126;U 0126 |
| Formal Name |
2,3-Bis[amino[(2-aminophenyl)thio]methylene]butanedinitrile |
| CAS Number |
109511-58-2 |
| Molecular Formula |
C18H16N6S2 |
| Formula Weight |
380.49 |
| Formulation |
A crystalline solid |
| Purity |
98%min |
| Stability |
2 years |
| Storage |
-20°C |
| Shipping |
USD45 for Europe and USA. No shipping charge once amount reach USD500 |
| Quality Control |
HNMR,CNMR,LCMS,HPLC,IR,etc. |
| Price & Availability |
In Stock. Price Negotiated. |
|
| Related Products： |
ERK/MAPK (Phospho-Thr202/Tyr204) Polyclonal Antibody
Kenpaullone
Olomoucine
p38 MAPK (Phospho-Thr180/Tyr182) Polyclonal Antibody
PD 169316
PD 98059
(R)-Roscovitine
SL 327
|
|
