| FABP4Inhibitor |
| 2-[[2’-(5-ethyl-3,4-diphenyl-1H-pyrazol-1-yl)[1,1’-biphenyl]-3-yl]oxy]-acetic acid |
| (CAS 300657-03-8) |
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| Description： |
Fatty acid binding protein 4 (FABP4) is a lipid transport protein that is also known as adipocyte FABP and aP2. In addition to adipocytes, it is also abundant in macrophages, along with FABP5, the epidermal FABP. FABP4 inhibitor is a cell-permeable, potent inhibitor of FABP4 that targets the fatty acid-binding pocket (Ki < 2 nM). It is less effective against FABP3 and FABP5 (Kis = 250 and 350 nM, respectively).2 FABP4 inhibitor is orally active, reducing atherosclerosis in mice lacking apoplipoprotein E. It also protects against the development of insulin resistance associated with genetic or diet-induced obesity in mice. FABP4 dose-dependently suppresses the release of MCP-1 from macrophages.
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| Product No. |
KT00354 |
| Product Name |
FABP4Inhibitor |
| Synonyms |
Adipocyte FABP Inhibitor,BMS 309403,aP2 Inhibitor,ALBP Inhibitor,Fatty Acid Binding Protein 4 Inhibitor,A-FABP Inhibitor |
| Formal Name |
2-[[2’-(5-ethyl-3,4-diphenyl-1H-pyrazol-1-yl)[1,1’-biphenyl]-3-yl]oxy]-acetic acid |
| CAS Number |
300657-03-8 |
| Molecular Formula |
C31H26N2O3 |
| Formula Weight |
474.6 |
| Formulation |
A crystalline solid |
| Purity |
98%min |
| Stability |
2 years |
| Storage |
-20°C |
| Shipping |
USD45 for Europe and USA. No shipping charge once amount reach USD500 |
| Quality Control |
HNMR,CNMR,LCMS,HPLC,IR,etc. |
| Price & Availability |
In Stock. Price Negotiated. |
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| Related Products： |
FABP4 (human) EIA Kit
FABP4 (human recombinant)
FABP4 (human recombinant) FITC conjugated
FABP4 Inhibitor/Ligand Screening Assay Kit
FABP4 (mouse recombinant)
FABP4 Polyclonal Antibody
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