| EVP4593 |
| N4-[2-(4-phenoxyphenyl)ethyl]-4,6-quinazolinediamine |
| (CAS 545380-34-5) |
 |
| Description： |
Nuclear factor-κB (NF-κB) is an ubiquitous transcription factor that functions to enhance the transcription of pro-inflammatory cytokines like TNF-α, IL-1β, IL-6, and IL-8. QNZ is an inhibitor of NF-κB activation with an IC50 of 11 nM in human Jurkat cells. It also inhibits TNF-α production from lipopolysaccharide-stimulated mouse splenocytes with an IC50 of 7 nM. QNZ showed efficacy in vivo by reducing edema formation in carrageenin-induced inflammation of rat hind paw.
|
| Product No. |
KT00351 |
| Product Name |
EVP4593 |
| Synonyms |
CAY10470 |
| Formal Name |
N4-[2-(4-phenoxyphenyl)ethyl]-4,6-quinazolinediamine |
| CAS Number |
545380-34-5 |
| Molecular Formula |
C22H20N4O |
| Formula Weight |
356.4 |
| Formulation |
A crystalline solid |
| Purity |
98%min |
| Stability |
2 years |
| Storage |
-20°C |
| Shipping |
USD45 for Europe and USA. No shipping charge once amount reach USD500 |
| Quality Control |
HNMR,CNMR,LCMS,HPLC,IR,etc. |
| Price & Availability |
In Stock. Price Negotiated. |
|
| Related Products： |
Andrographolide
CID-2858522
Emodin
JSH-23
Parthenolide
Sodium Salicylate
Triptolide
CID-2858522
HU-211
PPM-18
|
|
