| CYC202 |
| 2-(R)-(1-Ethyl-2-hydroxyethylamino)-6-benzylamino-9-isopropylpurine |
| (CAS 186692-46-6) |
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| Description： |
Biological Activity of Roscovitine (Seliciclib): Roscovitine (Seliciclib) is a potent and selective inhibitor of cyclin-dependent kinases (cdks). This agent displays higher inhibitory potency and higher selectivity compared to olomoucine.Roscovitine inhibits p34 cdc2/cyclin B (IC50 = 0.65 µM), p33 cdk2/cyclin A(IC50 = 0.70 µM), p33 cdk2/cyclin E (IC50 = 0.70 µM), and p33 cdk2/p35(IC50 = 0.20 µM) by competing for the ATP binding domain of these kinases. Roscovitine exhibits very low sensitivity towards related kinases, such as erk1 and erk2 (IC50 = 34 µM and 14 µM, respectively)
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| Product No. |
KT00320 |
| Product Name |
CYC202 |
| Synonyms |
Roscovitine,Seliciclib |
| Formal Name |
2-(R)-(1-Ethyl-2-hydroxyethylamino)-6-benzylamino-9-isopropylpurine |
| CAS Number |
186692-46-6 |
| Molecular Formula |
C19H26N6O |
| Formula Weight |
354.45 |
| Formulation |
A crystalline solid |
| Purity |
98%min |
| Stability |
2 years |
| Storage |
-20°C |
| Shipping |
USD45 for Europe and USA. No shipping charge once amount reach USD500 |
| Quality Control |
HNMR,CNMR,LCMS,HPLC,IR,etc. |
| Price & Availability |
In Stock. Price Negotiated. |
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CDK9-IN-2
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