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AEG 3482 
6-Phenylimidazo[2,1-b]-1,3,4-thiadiazole-2-sulfonamide
(CAS 63735-71-7)
Description:

Inhibitor of c-jun N-terminal kinase (JNK) signaling. Binds Hsp90 and facilitates HSF1 release, induces expression of Hsp70, which in turn blocks JNK activation and JNK-dependent apoptosis. Antiapoptotic; inhibits NGF withdrawal-induced death in SCG neurons (EC50 = 20 μM).

 

Product No. KT00042 
Product Name AEG 3482 
Synonyms
Formal Name 6-Phenylimidazo[2,1-b]-1,3,4-thiadiazole-2-sulfonamide
CAS Number 63735-71-7
Molecular Formula C10H8N4O2S2
Formula Weight 280.33
Formulation
Purity 98%min
Stability 1 year
Storage -20°C
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