| CAY10505 |
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| (CAS 1218777-13-9) |
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| Description： |
CAY10505 is a potent PI3K inhibitor with an IC50 of 30 nM. Phosphoinositide 3-kinase (PI3K) is expressed primarily in hematopoietic cells and plays several important roles in immunity. CAY10505 also prevents other , , and isoforms with IC50 of 0.94, 20, and 20 M, respectively. CAY10505 significantly inhibits only the unrelated casein kinase 2 (CK2, IC50 = 20 nM). CAY10505 also suppress the phosphorylation of the PI3K substrate PKB/Akt in murine macrophages (IC50 = 228 nM). Oral administration of CAY10505 decreases neutrophil recruitment in mice to an extent that is comparable to that observed in PI3K-deficient mice.
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| Product No. |
KT00244 |
| Product Name |
CAY10505 |
| Synonyms |
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| Formal Name |
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| CAS Number |
1218777-13-9 |
| Molecular Formula |
C14H8FNO3S |
| Formula Weight |
289.28 |
| Formulation |
A crystalline solid |
| Purity |
98%min |
| Stability |
2 years |
| Storage |
-20°C |
| Shipping |
USD45 for Europe and USA. No shipping charge once amount reach USD500 |
| Quality Control |
HNMR,CNMR,LCMS,HPLC,IR,etc. |
| Price & Availability |
In Stock. Price Negotiated. |
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