| BRL15572 |
| 3-(4-(4-chlorophenyl)piperazin-1-yl)-1,1-diphenyl-2-propanol |
| (CAS 193611-72-2) |
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| Description： |
BRL-15,572 is a drug which acts as a selective antagonist for the serotonin receptor subtype 5-HT1D, with around 60x selectivity over other related receptors. The 5-HT1D receptor has a very similar pharmacology to the closely related 5-HT1B receptor, and most older ligands for these receptors bind to both subtypes with approximately equal affinity, so development of compounds such as BRL-15572 which are able to selectively block the 5-HT1D subtype while leaving 5-HT1B unaffected, have been a significant advance which has helped scientists in researching the function of these serotonin receptor subtypes.[1][2] One function of the 5-HT1D receptor this research has revealed is its role in modulating release of the neurotransmitter glutamate in the brain,[3] as well as functions in regulation of cerebral blood pressure which are important in the pathogenesis of migraine headaches.[4]
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| Product No. |
KT00225 |
| Product Name |
BRL15572 |
| Synonyms |
|
| Formal Name |
3-(4-(4-chlorophenyl)piperazin-1-yl)-1,1-diphenyl-2-propanol |
| CAS Number |
193611-72-2 |
| Molecular Formula |
C25H28Cl2N2O |
| Formula Weight |
443.41 |
| Formulation |
A crystalline solid |
| Purity |
98%min |
| Stability |
2 years |
| Storage |
-20°C |
| Shipping |
USD45 for Europe and USA. No shipping charge once amount reach USD500 |
| Quality Control |
HNMR,CNMR,LCMS,HPLC,IR,etc. |
| Price & Availability |
In Stock. Price Negotiated. |
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