WY-14643 |
[4-Chloro-6-(2,3-xylidino)-2-pyrimidinylthio]acetic acid |
(CAS 50892-23-4) |
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Description: |
WY-14643 (Pirinixic Acid) is a potent peroxisome proliferator and activator of PPARα with EC50 of 1.5 μM.
WY-14643 is a peroxisome proliferator-activated receptor (PPAR activator). Although this compound is primarily an activator of PPARα,it activates PPARγ as well.Activation of PPARδ by Wy 14643 is also observed,but this finding is rare. The potency of Wy 14643 as an activator of PPARα is species dependent, with receptor activation occurring at concentrations as low as 0.1 µM in the mouse compared to 10 µM in Xenopus.
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Product No. |
KT00983 |
Product Name |
WY-14643 |
Synonyms |
NSC 310038; Pirinixic Acid; WY 14643; |
Formal Name |
[4-Chloro-6-(2,3-xylidino)-2-pyrimidinylthio]acetic acid |
CAS Number |
50892-23-4 |
Molecular Formula |
C14H14ClN3O2S |
Formula Weight |
323.80 |
Formulation |
A crystalline solid |
Purity |
98%min |
Stability |
2 years |
Storage |
-20°C |
Shipping |
USD45 for Europe and USA. No shipping charge once amount reach USD500 |
Quality Control |
HNMR,CNMR,LCMS,HPLC,IR,etc. |
Price & Availability |
In Stock. Price Negotiated. |
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