| BMS-345541 |
|
| (CAS 547757-23-3) |
 |
| Description: |
BMS-345541 is a highly selective inhibitor of the catalytic subunits of IKK-2 and IKK-1 with IC50 of 0.3 μM and 4 μM, respectively.
in vivo: BMS-345541 effectively inhibits melanoma tumor growth in a dose-dependent manner. Tumor-bearing mice treated with 75 mg/kg of BMS-345541 shows effective inhibition of growth of SK-MEL-5, A375, and Hs 294T tumors by 86 %, 69% and 67%, respectively, when compared with control animals treated with vehicle alone [2]. |
| Product No. |
KT00196 |
| Product Name |
BMS-345541 |
| Synonyms |
BMS-345541 HCl |
| Formal Name |
|
| CAS Number |
547757-23-3 |
| Molecular Formula |
C14H17N5.HCl |
| Formula Weight |
291.78 |
| Formulation |
A crystalline solid |
| Purity |
98%min |
| Stability |
2 years |
| Storage |
-20°C |
| Shipping |
USD45 for Europe and USA. No shipping charge once amount reach USD500 |
| Quality Control |
HNMR,CNMR,LCMS,HPLC,IR,etc. |
| Price & Availability |
In Stock. Price Negotiated. |
|
| Related Products: |
Bay 65-1942 free base
Bay 65-1942 hydrochloride
Bay 65-1942 R form
BMS-345541 free base
IKK 16
SC-514
TPCA-1
MLN120B |
|