| BIBR-1532 |
| 2-[[(2E)-3-(2-naphthalenyl)-1-oxo-2-buten-1-yl]amino]-benzoic acid |
| (CAS 321674-73-1) |
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| Description： |
BIBR 1532 is a mixed-type non-competitive inhibitor of telomerase (IC50 = 93 nM) that has little effect on several mammalian DNA and RNA polymerases, bacterial DNA helicase, or HIV-1 reverse transcriptase. It specifically targets the telomerase reverse transcriptase catalytic subunit, TERT. Through its effects on telomerase, BIBR 1532 induces senescence or apoptosis in cancer cells. Apoptosis in triple negative breast cancer cells induced by BIBR 1532 is potentiated by glucose restriction.
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| Product No. |
KT00177 |
| Product Name |
BIBR-1532 |
| Synonyms |
Telomerase Inhibitor X |
| Formal Name |
2-[[(2E)-3-(2-naphthalenyl)-1-oxo-2-buten-1-yl]amino]-benzoic acid |
| CAS Number |
321674-73-1 |
| Molecular Formula |
C21H17NO3 |
| Formula Weight |
331.4 |
| Formulation |
A crystalline solid |
| Purity |
98%min |
| Stability |
2 years |
| Storage |
-20°C |
| Shipping |
USD45 for Europe and USA. No shipping charge once amount reach USD500 |
| Quality Control |
HNMR,CNMR,LCMS,HPLC,IR,etc. |
| Price & Availability |
In Stock. Price Negotiated. |
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