| AS-1269574 |
| 2-[[2-(4-bromophenyl)-6-methyl-4-pyrimidinyl]amino]-ethanol |
| (CAS 330981-72-1) |
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| Description： |
GPR119, a glucose-dependent insulinotropic receptor, is a Gs protein-coupled receptor that is expressed in pancreas β-cells and intestinal L-cells. Activation of GPR119 by the endogenous ligands lyso-phosphatidylcholine and oleoyl ethanolamide increases intracellular cAMP levels and promotes glucose-stimulated insulin secretion. AS-1269574 is an agonist of GPR119 that is effective both in isolated cells and in vivo. It increases cAMP levels in HEK293 cells transfected with human GPR119 (EC50 = 2.5 μM) and glucose-stimulated insulin secretion in mice (100 mg/kg).
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| Product No. |
KT00095 |
| Product Name |
AS-1269574 |
| Synonyms |
|
| Formal Name |
2-[[2-(4-bromophenyl)-6-methyl-4-pyrimidinyl]amino]-ethanol |
| CAS Number |
330981-72-1 |
| Molecular Formula |
C13H14BrN3O |
| Formula Weight |
308.2 |
| Formulation |
A crystalline solid |
| Purity |
98%min |
| Stability |
2 years |
| Storage |
-20°C |
| Shipping |
USD45 for Europe and USA. No shipping charge once amount reach USD500 |
| Quality Control |
HNMR,CNMR,LCMS,HPLC,IR,etc. |
| Price & Availability |
In Stock. Price Negotiated. |
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| Related Products： |
Oleoyl Ethanolamide
PSN375963
PSN632408
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