| AZD2281 |
|
| (CAS 937799-91-2) |
 |
| Description： |
Poly(adenosine diphosphate-ribose) polymerase (PARP) is anenzyme that is involved in a specific kind of DNA repair called base-excision repair, which is used when there is an error in a strand of the DNA.IC50 :PARP-1= 0.005,PARP-2= 0.001 , PF50=25.8.AZD2281(Olaparib) at 400 mg twice daily is well tolerated and highly active. The toxicity that was seen in BRCA1/BRCA2 carriers was similar to the previously reported toxicity in noncarriers.
|
| Product No. |
KT00135 |
| Product Name |
AZD2281 |
| Synonyms |
|
| Formal Name |
|
| CAS Number |
937799-91-2 |
| Molecular Formula |
C24H23FN4O3 |
| Formula Weight |
434.46 |
| Formulation |
A crystalline solid |
| Purity |
98%min |
| Stability |
2 years |
| Storage |
-20°C |
| Shipping |
USD45 for Europe and USA. No shipping charge once amount reach USD500 |
| Quality Control |
HNMR,CNMR,LCMS,HPLC,IR,etc. |
| Price & Availability |
In Stock. Price Negotiated. |
|
| Related Products： |
A 966492
AZD2281 Olaparib
Fludarabine
Veliparib(ABT888)
Rucaparib (AG-014699,PF-01367338)
|
|
