| S-Adenosylmethionine |
| (2S)-2-Amino-4-[[(2S,3S,4R,5R)-5-(6-aminopurin-9-yl)-3,4-dihydroxyoxolan-2-yl]methyl-methylsulfonio]butanoate |
| (CAS 29908-03-0) |
 |
| Description： |
S-Adenosyl methionine (SAM-e, SAMe, SAM, S-Adenosyl-L-methionine, AdoMet, ademetionine) is a common cosubstrate involved in methyl group transfers. SAM was first discovered in Italy by G. L. Cantoni in 1952.It is made from adenosine triphosphate (ATP) and methionine by methionine adenosyltransferase (EC 2.5.1.6). Transmethylation, transsulfuration, and aminopropylation are the metabolic pathways that use SAM. Although these anabolic reactions occur throughout the body, most SAM is produced and consumed in the liver.
The methyl group (CH3) attached to the methionine sulfur atom in SAM is chemically reactive. This allows donation of this group to an acceptor substrate in transmethylation reactions. More than 40 metabolic reactions involve the transfer of a methyl group from SAM to various substrates, such as nucleic acids, proteins, lipids and secondary metabolites.
In bacteria, SAM is bound by the SAM riboswitch, which regulates genes involved in methionine or cysteine biosynthesis.
|
| Product No. |
KT10071 |
| Product Name |
S-Adenosylmethionine |
| Synonyms |
SAMe (S-Adenosyl-L-Methionine butanedisulfonate);Adenosine,5’-[(3-amino-3-carboxypropyl)methylsulfonio]-5’-deoxy-, hydroxide, inner salt,(3S)-;Adenosine, 5’-[(L-3-amino-3-carboxypropyl)methylsulfonio] |
| Formal Name |
(2S)-2-Amino-4-[[(2S,3S,4R,5R)-5-(6-aminopurin-9-yl)-3,4-dihydroxyoxolan-2-yl]methyl-methylsulfonio]butanoate |
| CAS Number |
29908-03-0 |
| Molecular Formula |
C15H22N6O5S |
| Formula Weight |
398.44 |
| Formulation |
A crystalline solid |
| Purity |
98%min |
| Stability |
2 years |
| Storage |
-20°C |
| Shipping |
USD45 for Europe and USA. No shipping charge once amount reach USD500 |
| Quality Control |
HNMR,CNMR,LCMS,HPLC,IR,etc. |
| Price & Availability |
In Stock. Price Negotiated. |
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