Z-VAD-FMK |
N-[(Phenylmethoxy)carbonyl]-L-valyl-N-[(1S)-3-fluoro-1-(2-methoxy-2-oxoethyl)-2-oxopropyl]-L-alaninamide |
(CAS 187389-52-2) |
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Description: |
Z-VAD(OMe)-FMK is a cell-permeable, competitive, and irreversible inhibitor of all caspases.Through this action, it inhibits cleavage of poly (ADP-ribose) polymerase, preventing apoptosis when used at 10-50 µM.It also blocks caspase-mediated apoptosis in vivo.Z-VAD(OMe)-FMK effectively prevents caspase action in inflammasomes. |
Product No. |
KT01021 |
Product Name |
Z-VAD-FMK |
Synonyms |
Z-Val-Ala-Asp-(OMe)-Fluoromethyl Ketone |
Formal Name |
N-[(Phenylmethoxy)carbonyl]-L-valyl-N-[(1S)-3-fluoro-1-(2-methoxy-2-oxoethyl)-2-oxopropyl]-L-alaninamide |
CAS Number |
187389-52-2 |
Molecular Formula |
C22H30FN3O7 |
Formula Weight |
467.49 |
Formulation |
A crystalline solid |
Purity |
98%min |
Stability |
1 year |
Storage |
-20°C |
Shipping |
USD45 for Europe and USA. No shipping charge once amount reach USD500. |
Quality Control |
HNMR,CNMR,LCMS,HPLC,IR,etc. |
Price & Availability |
In Stock. Price Negotiated. |
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