| Busulfan |
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| (CAS 55-98-1) |
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| Description： |
Busulfan is a bifunctional alkylating agent.
Target: DNA alkylator
Busulfan, a cytotoxic alkylating agent used for treatment of chronic myeloid leukemia has effects in mammalian germ cells [1]. Busulfan is bifunctional and thus may effectively induce DNA damage, which may play an important role in the cytotoxicity. Busulfan induced DNA damage dose-dependently. busulfan caused double-base lesions mainly at 5'-GA-3' and, to a lesser extent, at 5'-GG-3' sequences [2].
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| Product No. |
KT20776 |
| Product Name |
Busulfan |
| Synonyms |
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| Formal Name |
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| CAS Number |
55-98-1 |
| Molecular Formula |
C6H14O6S2 |
| Formula Weight |
246.3 |
| Formulation |
A crystalline solid |
| Purity |
98%min |
| Stability |
2 years |
| Storage |
-20°C |
| Shipping |
USD45 for Europe and USA. No shipping charge once amount reach USD500 |
| Quality Control |
HNMR,CNMR,LCMS,HPLC,IR,etc. |
| Price & Availability |
In Stock. Price Negotiated. |
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| Related Products： |
Altretamine
Altretamine is an alkylating agent proposed as an antineoplastic.
Target: DNA alkylator
Altretamine represents a useful alternative in patients who prefer oral treatment or when socioeconomic considerations are an important issue. Altretamine is an acceptable and apparently less toxic alternative to other cytotoxic drugs used for palliation of patients with recurrent epithelial ovarian cancer. The inter-hand intrapatient variability of the bioavailability of altretamine after oral administration represents an important drawback for effective clinical use of this drug. The variability appears to be mostly related to the first-pass effect and therefore may be overcome by intravenous administration of the drug.
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