| NVP-BBD130 |
| 2-Methyl-2-[4-[3-methyl-2-oxo-8-[(pyridin-3-yl)ethynyl]-2,3-dihydroimidazo[4,5-c]quinolin-1-yl]phenyl]propionitrile |
| (CAS 853910-61-9) |
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| Description： |
Orally potent and selective dual PI3K/mTOR inhibitor.
IC50 values to be 72, 2336, 201 and 382 nM for PI3K p110 alpha, beta, delta and gamma isoforms, respectively; inhibition of PI3K/mTOR pathway like NVP-BEZ235, BBD130 efficiently attenuates growth and proliferation of melanoma primary tumors and metastasis.
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| Product No. |
KT00609 |
| Product Name |
NVP-BBD130 |
| Synonyms |
NVP-BBD 130 |
| Formal Name |
2-Methyl-2-[4-[3-methyl-2-oxo-8-[(pyridin-3-yl)ethynyl]-2,3-dihydroimidazo[4,5-c]quinolin-1-yl]phenyl]propionitrile |
| CAS Number |
853910-61-9 |
| Molecular Formula |
C28H21N5O |
| Formula Weight |
443.50 |
| Formulation |
A crystalline solid |
| Purity |
98%min |
| Stability |
2 years |
| Storage |
-20°C |
| Shipping |
USD45 for Europe and USA. No shipping charge once amount reach USD500 |
| Quality Control |
HNMR,CNMR,LCMS,HPLC,IR,etc. |
| Price & Availability |
In Stock. Price Negotiated. |
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