| AVL292 |
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| (CAS 1202757-89-8) |
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| Description： |
AVL-292 is a covalent, highly selective, orally active small molecule inhibitor of Btk with IC50 value of 0.5 nM; >1400-fold selectivity over the other kinases assayed.
AVL-292 is currently being evaluated in a Phase 1b clinical trial in relapsed, refractory B cell malignancies including Chronic Lymphocytic Leukemia (CLL) and non-Hodgkin lymphomas.
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| Product No. |
KT00120 |
| Product Name |
AVL292 |
| Synonyms |
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| Formal Name |
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| CAS Number |
1202757-89-8 |
| Molecular Formula |
C22H22FN5O3 |
| Formula Weight |
423.44 |
| Formulation |
A crystalline solid |
| Purity |
98%min |
| Stability |
2 years |
| Storage |
-20°C |
| Shipping |
USD45 for Europe and USA. No shipping charge once amount reach USD500 |
| Quality Control |
HNMR,CNMR,LCMS,HPLC,IR,etc. |
| Price & Availability |
In Stock. Price Negotiated. |
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| Related Products： |
Btk inhibitor 1
AVL-292 benzenesulfonate
CGI-1746
CNX-774
GDC-0834
PCI 29732
PCI-32765
QL47
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