| AB-001 |
| (1s,3s)-adamantan-1-yl(1-pentyl-1H-indol-3-yl)methanone |
| (CAS 1345973-49-0) |
 |
| Description： |
AB-001 or 1-pentyl-3-(1-adamantoyl)indole is a designer drug that was found as an ingredient in synthetic cannabis smoking blends in Ireland in 2010 and Hungary and Germany in 2011.[1][2][3] It is unclear who AB-001 was originally developed by, but it is structurally related to compounds such as AM-1248 and its corresponding 1-(tetrahydropyran-4-ylmethyl) analogue, which are known to be potent cannabinoid agonists with moderate to high selectivity for CB2 over CB1.[4][5] The first published synthesis and pharmacological evaluation of AB-001 revealed that it acts as a full agonist at CB1 (EC50 = 35 nM) and CB2 receptors (EC50 = 48 nM).[6] However, AB-001 was found to possess only weak cannabimimetic effects in rats at doses up to 30 mg/kg, making it less potent than carboxamide analogue SDB-001, which possesses potent cannabimimetic activity at doses of 3 mg/kg.[6] |
| Product No. |
KT00021 |
| Product Name |
AB-001 |
| Synonyms |
|
| Formal Name |
(1s,3s)-adamantan-1-yl(1-pentyl-1H-indol-3-yl)methanone |
| CAS Number |
1345973-49-0 |
| Molecular Formula |
C24H31NO |
| Formula Weight |
349.5 |
| Formulation |
A crystalline solid |
| Purity |
98%min |
| Stability |
1 year |
| Storage |
-20°C |
| Shipping |
USD45 for Europe and USA. No shipping charge once amount reach USD500. |
| Quality Control |
HNMR,CNMR,LCMS,HPLC,IR,etc. |
| Price & Availability |
In Stock. Price Negotiated. |
|
| Related Products： |
THJ 018
JWH 370
JWH 145
AM679
AM1248 |
|
