| A 966492 |
|
| (CAS 934162-61-5) |
 |
| Description： |
A-966492 is one of the most potent PARP inhibitors. A-966492 displays excellent potency against the PARP-1 enzyme with a Kiof 1 nM and an EC50 of 1 nM in a whole cell assay. A-966492 significantly enhances the efficacy of TMZ in a dose-dependent manner. In addition, A-966492 is orally bioavailable across multiple species, crosses the blood−brain barrier, and appears to distribute into tumor tissue. A-966492 represents a promising, structurally diverse benzimidazole analogue and is being further characterized preclinically. |
| Product No. |
KT00019 |
| Product Name |
A 966492 |
| Synonyms |
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| Formal Name |
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| CAS Number |
934162-61-5 |
| Molecular Formula |
C18H17FN4O |
| Formula Weight |
324.35 |
| Formulation |
|
| Purity |
98%min |
| Stability |
1 year |
| Storage |
-20°C |
| Shipping |
USD45 for Europe and USA. No shipping charge once amount reach USD500. |
| Quality Control |
HNMR,CNMR,LCMS,HPLC,IR,etc. |
| Price & Availability |
In Stock. Price Negotiated. |
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BSI-201 |
|
