| Pentostatin |
| (8R)-3-(2-deoxy-β-D-erythro-pentofuranosyl)-3,4,7,8-tetrahydro-imidazo[4,5-d][1,3]diazepin-8-ol |
| (CAS 53910-25-1) |
 |
| Description： |
Pentostatin is an irreversible inhibitor of adenosine deaminase (Ki = 2.5 pM).
Because of their antitumor activity via inhibition of DNA synthesis, purine nucleoside derivatives resistant to deamination have been developed for the treatment of various leukemias.Pentostatin is a purine nucleoside analog that irreversibly inhibits adenosine deaminase (Ki = 0.9 pM) and thus interrupts DNA synthesis in dividing cells.Pentostatin has been reported to display strong efficacy in the clinical treatment of hairy cell leukemia as well as relapsed chronic lymphocytic leukemia.
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| Product No. |
KT00660 |
| Product Name |
Pentostatin |
| Synonyms |
DCF；CL 67310465;NSC 247520;Deoxycoformycin;NSC 218321;CI 825 |
| Formal Name |
(8R)-3-(2-deoxy-β-D-erythro-pentofuranosyl)-3,4,7,8-tetrahydro-imidazo[4,5-d][1,3]diazepin-8-ol |
| CAS Number |
53910-25-1 |
| Molecular Formula |
C11H16N4O4 |
| Formula Weight |
268.27 |
| Formulation |
A crystalline solid |
| Purity |
98%min |
| Stability |
2 years |
| Storage |
-20°C |
| Shipping |
USD45 for Europe and USA. No shipping charge once amount reach USD500 |
| Quality Control |
HNMR,CNMR,LCMS,HPLC,IR,etc. |
| Price & Availability |
In Stock. Price Negotiated. |
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