| Dacomitinib |
| (2E)-N-[4-[(3-Chloro-4-fluorophenyl)amino]-7-methoxy-6-quinazolinyl]-4-(1-piperidinyl)-2-butenamide hydrate (1:1) |
| (CAS 1042385-75-0) |
 |
| Description： |
Dacomitinib is a potent, irreversible pan-ErbB inhibitor, mostly to EGFR with IC50 of 6 nM, effective against NSCLCs with EGFR or ERBB2 mutations (resistant to gefitinib) as well as those harboring the EGFR T790M mutation.
|
| Product No. |
KT00676 |
| Product Name |
Dacomitinib |
| Synonyms |
PF299804, PF299 |
| Formal Name |
(2E)-N-[4-[(3-Chloro-4-fluorophenyl)amino]-7-methoxy-6-quinazolinyl]-4-(1-piperidinyl)-2-butenamide hydrate (1:1) |
| CAS Number |
1042385-75-0 |
| Molecular Formula |
C24H25ClFN5O2.H2O |
| Formula Weight |
487.95 |
| Formulation |
A crystalline solid |
| Purity |
98%min |
| Stability |
2 years |
| Storage |
-20°C |
| Shipping |
USD45 for Europe and USA. No shipping charge once amount reach USD500 |
| Quality Control |
HNMR,CNMR,LCMS,HPLC,IR,etc. |
| Price & Availability |
In Stock. Price Negotiated. |
|
| Related Products： |
CO-1686
AZD9291
EMD 1214063
OSI-744
ZD-1839
BIBW2992
Lapatinib
AG-490
AG-1478
WZ4002
|
|
