| PJ-34 hydrochloride |
| N-(6-Oxo-5,6-dihydrophenanthridin-2-yl)-2-(N,N-dimethylamino)acetamide hydrochloride |
| (CAS 344458-15-7) |
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| Description： |
PJ-34 hydrochloride is a novel potent specific inhibitor of PARP-l/2 with EC50 of 20 nM.
The poly(ADP-ribose) polymerases (PARPs) form a family of enzymes with roles in DNA repair and apoptosis, particularly in response to reactive oxygen and nitrogen species.PJ-34 is an inhibitor of PARPs which can be used in cells or in animals.It binds and inhibits the PARP tankyrase1 (IC50 = 1 μM).PJ-34 also inhibits matrix metalloproteinase-2 when used at higher concentrations (IC50 = 56 μM).
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| Product No. |
KT00705 |
| Product Name |
PJ-34 hydrochloride |
| Synonyms |
PJ34 hydrochloride;PJ 34 hydrochloride |
| Formal Name |
N-(6-Oxo-5,6-dihydrophenanthridin-2-yl)-2-(N,N-dimethylamino)acetamide hydrochloride |
| CAS Number |
344458-15-7 |
| Molecular Formula |
C17H17N3O2.HCl |
| Formula Weight |
331.80 |
| Formulation |
A crystalline solid |
| Purity |
98%min |
| Stability |
2 years |
| Storage |
-20°C |
| Shipping |
USD45 for Europe and USA. No shipping charge once amount reach USD500 |
| Quality Control |
HNMR,CNMR,LCMS,HPLC,IR,etc. |
| Price & Availability |
In Stock. Price Negotiated. |
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