| PNU282987 |
| N-(3R)-1-Azabicyclo[2.2.2]oct-3-yl-4-chlorobenzamide hydrochloride |
| (CAS 123464-89-1) |
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| Description： |
PNU282987 is a highly selective agonist for the homomeric α7 nicotinic acetylcholine receptor (α7 nAChR).
This novel agonist of the α7 nAChR has been utilized in multiple model brain investigations of this receptor. Utilizing rat hippocampal slices PNU282987 has been reported to evoke whole-cell currents. PNU282987 is hypothesized to modulate or enhance GABAergic hippocampal neurotransmission. Additionally, in mouse cerebellum, ethanol-induced ataxia was attenuated in a dose-dependant fashion with administration of PNU282987. PNU282987 has also been used in various studies to investigate the effects of the compound on hippocampal theta oscillation.
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| Product No. |
KT00714 |
| Product Name |
PNU282987 |
| Synonyms |
PNU 282987;PNU-282987 |
| Formal Name |
N-(3R)-1-Azabicyclo[2.2.2]oct-3-yl-4-chlorobenzamide hydrochloride |
| CAS Number |
123464-89-1 |
| Molecular Formula |
C14H17ClN2O.HCl |
| Formula Weight |
301.22 |
| Formulation |
A crystalline solid |
| Purity |
98%min |
| Stability |
2 years |
| Storage |
-20°C |
| Shipping |
USD45 for Europe and USA. No shipping charge once amount reach USD500 |
| Quality Control |
HNMR,CNMR,LCMS,HPLC,IR,etc. |
| Price & Availability |
In Stock. Price Negotiated. |
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