| PNU 74654 |
| 2-[(5-methyl-2-furanyl)methylene]hydrazide-2-phenoxy-benzoic acid |
| (CAS 113906-27-7) |
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| Description： |
2-[(5-methyl-2-furanyl)methylene]hydrazide-2-phenoxy-benzoic acidThe Wnt signaling pathway is integral to normal biological processes and inappropriately active in many cancers.PNU 74654 binds to β-catenin (KD = 450 nM), inhibiting its interaction with the transcription factor T-cell factor 4 (Tcf4) resulting in disruption of the Wnt signaling pathway.Treatment of human adrenocortical cell lines with PNU 74654 significantly reduced expression of several Tcf/β-catenin target genes.
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| Product No. |
KT00715 |
| Product Name |
PNU 74654 |
| Synonyms |
PNU74654;PNU-74654 |
| Formal Name |
2-[(5-methyl-2-furanyl)methylene]hydrazide-2-phenoxy-benzoic acid |
| CAS Number |
113906-27-7 |
| Molecular Formula |
C19H16N2O3 |
| Formula Weight |
320.34 |
| Formulation |
A crystalline solid |
| Purity |
98%min |
| Stability |
2 years |
| Storage |
-20°C |
| Shipping |
USD45 for Europe and USA. No shipping charge once amount reach USD500 |
| Quality Control |
HNMR,CNMR,LCMS,HPLC,IR,etc. |
| Price & Availability |
In Stock. Price Negotiated. |
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