| AMG-706 |
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| (CAS 857876-30-3) |
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| Description： |
Motesanib (AMG-706) is an orally bioavailable diphosphate salt of a multiple receptor tyrosine kinase inhibitor with potential antineoplastic activity[1]. This reagent selectively targets and inhibits VEGFR1/2/3(IC50: 2 nM /3 nM /6 nM), PDGFR (84nM), kit (8nM), and Ret (59nM)receptors, thereby inhibiting angiogenesis and cellular proliferation. Oral administration of AMG 706 potently inhibited VEGF-induced angiogenesis in the rat corneal model and induced regression of established A431 xenografts
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| Product No. |
KT00076 |
| Product Name |
AMG-706 |
| Synonyms |
Motesanib |
| Formal Name |
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| CAS Number |
857876-30-3 |
| Molecular Formula |
C22H29N5O9P2 |
| Formula Weight |
569.44 |
| Formulation |
A crystalline solid |
| Purity |
98%min |
| Stability |
2 years |
| Storage |
-20°C |
| Shipping |
USD45 for Europe and USA. No shipping charge once amount reach USD500 |
| Quality Control |
HNMR,CNMR,LCMS,HPLC,IR,etc. |
| Price & Availability |
In Stock. Price Negotiated. |
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| Related Products： |
Amuvatinib
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Axitinib
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BMS-690514
DCC-2618
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