Pregnenolone |
3β-Hydroxy-5-pregnen-20-one |
(CAS 145-13-1) |
 |
Description: |
Pregnenolone is an endogenous steroid hormone for inhibition of M1 receptor and M3 receptor-mediated currents with IC50 of 11.4 μM and 6.0 μM, respectively.
Target: M1 receptor; M3 receptor
Pregnenolone is an endogenous steroid hormone involved in the steroidogenesis of progestogens, mineralocorticoids, glucocorticoids, androgens, and estrogens, as well as the neuroactive steroids.
Pregnenolone and its sulfate, like DHEA and its sulfate and progesterone, belong to the group of neurosteroids that are found in high concentrations in certain areas of the brain, and are synthesized there. Neurosteroids affect synaptic functioning, are neuroprotective, and enhance myelinization. Pregnenolone and its sulfate ester are under investigation for their potential to improve cognitive and memory functioning. Pregnenolone is also being considered as a potential treatment for schizophrenia.
|
Product No. |
KT20438 |
Product Name |
Pregnenolone |
Synonyms |
Arthenolone |
Formal Name |
3β-Hydroxy-5-pregnen-20-one |
CAS Number |
145-13-1 |
Molecular Formula |
C21H32O2 |
Formula Weight |
316.48 |
Formulation |
A crystalline solid |
Purity |
98%min |
Stability |
2 years |
Storage |
-20°C |
Shipping |
USD45 for Europe and USA. No shipping charge once amount reach USD500 |
Quality Control |
HNMR,CNMR,LCMS,HPLC,IR,etc. |
Price & Availability |
In Stock. Price Negotiated. |
|
Related Products: |
mAChR
Pilocarpine Hydrochloride
Scopolamine hydrobromide
Solifenacin hydrochloride
Tarafenacin
Tiotropium Bromide
Tolterodine Tartrate
Tropicamide
Umeclidinium bromide
VU0152100
Xanomeline oxalate
|
|