Scopolamine butylbromide |
(-)-N-Butylscopolamine bromide; Hyoscine N-butyl bromide |
(CAS 149-64-4) |
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Description: |
Scopolamine butylbromide is a competitive antagonist of muscarinic acetylcholine receptor (mAChR) with an IC50 of 55.3 ± 4.3 nM.
Target: mAChR
Scopolamine (USAN), also known as levo-duboisine and hyoscine, sold as Scopoderm, is a tropane alkaloid drug with muscarinic antagonist effects. It is among the secondary metabolites of plants from Solanaceae (nightshade) family of plants, such as henbane, jimson weed (Datura), angel's trumpets (Brugmansia), and corkwood (Duboisia). Scopolamine exerts its effects by acting as a competitive antagonist at muscarinic acetylcholine receptors, specifically M1 receptors; it is thus classified as an anticholinergic, antimuscarinic drug.
Its use in medicine is relatively limited, with its chief uses being in the treatment of motion sickness and postoperative nausea and vomiting. Scopolamine is named after the plant genus Scopolia. The name "hyoscine" is from the scientific name for henbane, Hyoscyamus niger.
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Product No. |
KT20408 |
Product Name |
Scopolamine butylbromide |
Synonyms |
Hyoscine butylbromide; Buscopan; (-)-Scopolamine butylbromide; Butylscopolammonium bromide; Butylscopolamine bromide |
Formal Name |
(-)-N-Butylscopolamine bromide; Hyoscine N-butyl bromide |
CAS Number |
149-64-4 |
Molecular Formula |
C21H30BrNO4 |
Formula Weight |
440.37 |
Formulation |
A crystalline solid |
Purity |
98%min |
Stability |
2 years |
Storage |
-20°C |
Shipping |
USD45 for Europe and USA. No shipping charge once amount reach USD500 |
Quality Control |
HNMR,CNMR,LCMS,HPLC,IR,etc. |
Price & Availability |
In Stock. Price Negotiated. |
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