| MDA 19 |
| (2Z)-2-(1-hexyl-1,2-dihydro-2-oxo-3H-indol-3-ylidene)hydrazide, benzoic acid |
| (CAS 1048973-47-2) |
 |
| Description： |
MDA 19 is a selective agonist of the human peripheral cannabinoid (CB2) receptor, with an EC50 value for activation (63.4 nM) that is 14-fold lower than that for central cannabinoid (CB1) activation (EC50 = 867 nM). Surprisingly, it acts as an inverse agonist at the rat CB2 receptor in cell-based functional assays. MDA19 attenuates tactile allodynia produced by spinal nerve ligation or paclitaxel in a dose-related manner in rats and in CB2 +/+ mice but not in CB2 -/- mice, indicating that CB2 receptors mediated the effects of MDA19. These effects of MDA 19 are blocked by the selective CB2 antagonist AM630. |
| Product No. |
KT00547 |
| Product Name |
MDA 19 |
| Synonyms |
MDA19; MDA-19 |
| Formal Name |
(2Z)-2-(1-hexyl-1,2-dihydro-2-oxo-3H-indol-3-ylidene)hydrazide, benzoic acid |
| CAS Number |
1048973-47-2 |
| Molecular Formula |
C21H23N3O2 |
| Formula Weight |
349.4 |
| Formulation |
A crystalline solid |
| Purity |
98%min |
| Stability |
2 years |
| Storage |
-20°C |
| Shipping |
USD45 for Europe and USA. No shipping charge once amount reach USD500 |
| Quality Control |
HNMR,CNMR,LCMS,HPLC,IR,etc. |
| Price & Availability |
In Stock. Price Negotiated. |
|
| Related Products： |
AM630
BML-190
JWH 073
Org 27569
Otenabant
PB-22
Taranabant |
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