| MBX-2982 |
| 5-ethyl-2-(4-(4-(((4-(1h-tetrazol-1-yl)phenyl)oxy)methyl)thiazol-2-yl)piperidin-1-yl)pyrimidine |
| (CAS 1037792-44-1) |
 |
| Description： |
MBX-2982 is a selective, orally-available GPR119 agonist for the treatment of type 2 tiabetes.
MBX-2982 is a potential first-in-class treatment for type 2 diabetes that targets G protein-coupled receptor 119 (GPR119), a receptor that interacts with bioactive lipids known to stimulate glucose-dependent insulin secretion. Preclinical data indicate that MBX-2982 is a potent selective orally-active GPR119 agonist that functions through a unique dual mechanism of action. First, it acts directly on the beta cell to increase insulin secretion. In addition, MBX-2982 stimulates release of the incretin GLP-1 from the gut. This dual action is unique and may offer improved glucose homeostasis over existing diabetes therapies, with potential for weight loss and improved islet health. |
| Product No. |
KT00546 |
| Product Name |
MBX-2982 |
| Synonyms |
MBX 2982; MBX2982 |
| Formal Name |
5-ethyl-2-(4-(4-(((4-(1h-tetrazol-1-yl)phenyl)oxy)methyl)thiazol-2-yl)piperidin-1-yl)pyrimidine |
| CAS Number |
1037792-44-1 |
| Molecular Formula |
C22H24N8OS |
| Formula Weight |
448.54396 |
| Formulation |
A crystalline solid |
| Purity |
98%min |
| Stability |
2 years |
| Storage |
-20°C |
| Shipping |
USD45 for Europe and USA. No shipping charge once amount reach USD500 |
| Quality Control |
HNMR,CNMR,LCMS,HPLC,IR,etc. |
| Price & Availability |
In Stock. Price Negotiated. |
|
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