LY2940680 |
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(CAS 1258861-20-9) |
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Description: |
Smoothened (Smo) is a GPCR-like receptor that, with Patched, mediates hedgehog (Hh) signaling to regulate gene expression through the Gli transcription factors. LY2940680 is an antitumor agent that binds to the human Smo receptor and inhibits Sonic Hh-induced Gli1 expression (IC50 = ~2.4 nM in vitro). The potential anticancer activity of LY2940680 is currently under clinical investigation.
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Product No. |
KT00528 |
Product Name |
LY2940680 |
Synonyms |
Taladegib |
Formal Name |
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CAS Number |
1258861-20-9 |
Molecular Formula |
C26H24F4N6O |
Formula Weight |
512.5 |
Formulation |
A crystalline solid |
Purity |
98%min |
Stability |
2 years |
Storage |
-20°C |
Shipping |
USD45 for Europe and USA. No shipping charge once amount reach USD500 |
Quality Control |
HNMR,CNMR,LCMS,HPLC,IR,etc. |
Price & Availability |
In Stock. Price Negotiated. |
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