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LY171883 
1-​[2-​hydroxy-​3-​propyl-​4-​[4-​(1H-​tetrazol-​5-​yl)butoxy]phenyl]-​ethanone
(CAS 88107-10-2)
Description:

LY171883 is a selective, potent, orally active antagonist of the leukotriene D4 receptor. Dissociation constants (KB) for LY171883 on guinea pig ileum and parenchyma are 0.07 and 0.34 µM, respectively. LY171883 is an inhibitor of phosphodiesterase obtained from human polymorphonuclear leukocytes (IC50 of 22.6 µM) and various guinea pig tissues (IC50s range from 6.9-209 µM). At a concentration of 50-100 µM, LY171883 binds to the PPARγ nuclear receptor, inducing adipogenesis in cultured NIH3T3 fibroblasts.

 

Product No. KT00507 
Product Name LY171883 
Synonyms
Formal Name 1-​[2-​hydroxy-​3-​propyl-​4-​[4-​(1H-​tetrazol-​5-​yl)butoxy]phenyl]-​ethanone
CAS Number 88107-10-2
Molecular Formula C16H22N4O3
Formula Weight 318.4
Formulation A crystalline solid
Purity 98%min
Stability 2 years
Storage -20°C
Shipping USD45 for Europe and USA. No shipping charge once amount reach USD500
Quality Control HNMR,CNMR,LCMS,HPLC,IR,etc.
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