| Mitoxantrone dihydrochloride |
| 1,4-dihydroxy-5,8-bis[[2-[(2-hydroxyethyl)amino]ethyl]amino]-9,10-anthracenedione, dihydrochloride |
| (CAS 70476-82-3) |
 |
| Description： |
Mitoxantrone Dihydrochloride, a type II topoisomerase inhibitor, is an anthracenedione-derived antineoplastic agent.
Target: Topoisomerase II
Mitoxantrone is an anthracenedione antineoplastic agent. Mitoxantrone is a type II topoisomerase inhibitor; it disrupts DNA synthesis and DNA repair in both healthy cells and cancer cells, by intercalation.Mitoxantrone is used in the treatment of certain types of cancer, mostly metastatic breast cancer, acute myeloid leukemia, and non-Hodgkin's lymphoma. It was also shown to improve the survival of children suffering from first relapse of acute lymphoblastic leukaemia.Mitoxantrone is also used to treat multiple sclerosis (MS), most notably the subset known as secondary progressive MS. Mitoxantrone will not cure multiple sclerosis, but is effective in slowing the progression of secondary progressive MS and extending the time between relapses in relapsing-remitting MS and progressive relapsing MS. |
| Product No. |
KT20058 |
| Product Name |
Mitoxantrone dihydrochloride |
| Synonyms |
Novantrone dihydrochloride; mitozantrone dihydrochloride |
| Formal Name |
1,4-dihydroxy-5,8-bis[[2-[(2-hydroxyethyl)amino]ethyl]amino]-9,10-anthracenedione, dihydrochloride |
| CAS Number |
70476-82-3 |
| Molecular Formula |
C22H30Cl2N4O6 |
| Formula Weight |
517.4 |
| Formulation |
A crystalline solid |
| Purity |
98%min |
| Stability |
2 years |
| Storage |
-20°C |
| Shipping |
USD45 for Europe and USA. No shipping charge once amount reach USD500 |
| Quality Control |
HNMR,CNMR,LCMS,HPLC,IR,etc. |
| Price & Availability |
In Stock. Price Negotiated. |
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