Hydrocortisone |
11-beta,17-alpha,21-trihydroxypregn-4-ene-3,20-dione |
(CAS 50-23-7) |
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Description: |
Hydrocortisone is a main glucocorticoid secreted by the adrenal cortex.
Target: Glucocorticoid Receptor
Hydrocortisone as an anti-inflammatory and immuno-suppressant agent has multiple mechanisms of action. Hydrocortisone significantly reduced monocyte expression of hTLR4 in test group (P<0.01). In addition, it had a significant effect on reduction of serum concentrations of TNF-α and IL-1β in test group in a time-dependent manner (P<0.01). Conclusion: In this study, hydrocortisone was able to reduce the hTLR4/CD14 positive monocytes and its related pro-inflammatory cytokines, thus it can decrease inflammatory responses following PCI.
Hydrocortisone dose was negatively associated with predicted AH, with each mg/m2/day increase in average growth period Hydrocortisone dose predicting a 0.37-cm decrease in AH (P < .004).
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Product No. |
KT20399 |
Product Name |
Hydrocortisone |
Synonyms |
Cortisol; D-Mannopyranose |
Formal Name |
11-beta,17-alpha,21-trihydroxypregn-4-ene-3,20-dione |
CAS Number |
50-23-7 |
Molecular Formula |
C21H30O5 |
Formula Weight |
362.46 |
Formulation |
A crystalline solid |
Purity |
98%min |
Stability |
2 years |
Storage |
-20°C |
Shipping |
USD45 for Europe and USA. No shipping charge once amount reach USD500 |
Quality Control |
HNMR,CNMR,LCMS,HPLC,IR,etc. |
Price & Availability |
In Stock. Price Negotiated. |
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