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Hydrocortisone 
11-beta,17-alpha,21-trihydroxypregn-4-ene-3,20-dione
(CAS 50-23-7)
Description:

Hydrocortisone is a main glucocorticoid secreted by the adrenal cortex.
Target: Glucocorticoid Receptor
Hydrocortisone as an anti-inflammatory and immuno-suppressant agent has multiple mechanisms of action. Hydrocortisone significantly reduced monocyte expression of hTLR4 in test group (P<0.01). In addition, it had a significant effect on reduction of serum concentrations of TNF-α and IL-1β in test group in a time-dependent manner (P<0.01). Conclusion: In this study, hydrocortisone was able to reduce the hTLR4/CD14 positive monocytes and its related pro-inflammatory cytokines, thus it can decrease inflammatory responses following PCI.
Hydrocortisone dose was negatively associated with predicted AH, with each mg/m2/day increase in average growth period Hydrocortisone dose predicting a 0.37-cm decrease in AH (P < .004).

 

Product No. KT20399 
Product Name Hydrocortisone 
Synonyms Cortisol; D-Mannopyranose
Formal Name 11-beta,17-alpha,21-trihydroxypregn-4-ene-3,20-dione
CAS Number 50-23-7
Molecular Formula C21H30O5
Formula Weight 362.46
Formulation A crystalline solid
Purity 98%min
Stability 2 years
Storage -20°C
Shipping USD45 for Europe and USA. No shipping charge once amount reach USD500
Quality Control HNMR,CNMR,LCMS,HPLC,IR,etc.
Price & Availability In Stock. Price Negotiated.
 
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