| AMG 9810 |
| N-tricyclo[3.3.1.13,7]dec-1-yl-2-quinoxalinecarboxamide |
| (CAS 545395-94-6) |
 |
| Description： |
AMG 9810 is a competitive antagonist of capsaicin activation of the vanilloid receptor 1 (TRPV1) (IC50s = 24.5 and 85.6 nM for human and rat, respectively). Additionally, it has been shown to compete with other modes of TRPV1 activation, including protons (IC50s = 92.7 and 294 nM for human and rat, respectively), heat (IC50s = 15.8 and 21 nM for human and rat, respectively), and the endogenous ligands: anandamide, N-arachidonyl dopamine (IC50s = 8.5 and 260 nM for human and rat, respectively), and oleoyldopamine. In a rat model of inflammatory pain induced by intraplantar injection of complete Freund’s adjuvant, 30-100 mg/kg AMG 9810 reverses thermal and mechanical hyperalgesia. |
| Product No. |
KT00079 |
| Product Name |
AMG 9810 |
| Synonyms |
|
| Formal Name |
N-tricyclo[3.3.1.13,7]dec-1-yl-2-quinoxalinecarboxamide |
| CAS Number |
545395-94-6 |
| Molecular Formula |
C21H23NO3 |
| Formula Weight |
337.4 |
| Formulation |
A crystalline solid |
| Purity |
98%min |
| Stability |
2 years |
| Storage |
-20°C |
| Shipping |
USD45 for Europe and USA. No shipping charge once amount reach USD500 |
| Quality Control |
HNMR,CNMR,LCMS,HPLC,IR,etc. |
| Price & Availability |
In Stock. Price Negotiated. |
|
| Related Products： |
5'-Iodoresiniferatoxin
CAY10448
Docosahexaenoyl Serotonin
Eicosapentaenoyl Serotonin
Oleoyl Serotonin
Oleoyl Serotonin-d17
Palmitoyl Serotonin
SB 366791
Stearoyl Serotonin |
|
