| LDN57444 |
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| (CAS 668467-91-2) |
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| Description： |
LDN-57444 is a reversible, competitive proteasome inhibitor for Uch-L1 with IC50 of 0.88 μM, 28-fold selectivity over isoform Uch-L3.
LDN-57444 causes dramatic alterations in synaptic protein distribution and spine morphology in vivo. Treatment with LDN also results in a rapid fall of Uch-L1 activity, but proteasome inhibition has no effect on cAMP levels over a period of several hours.
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| Product No. |
KT00498 |
| Product Name |
LDN57444 |
| Synonyms |
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| Formal Name |
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| CAS Number |
668467-91-2 |
| Molecular Formula |
C17H11Cl3N2O3 |
| Formula Weight |
397.64 |
| Formulation |
A crystalline solid |
| Purity |
98%min |
| Stability |
2 years |
| Storage |
-20°C |
| Shipping |
USD45 for Europe and USA. No shipping charge once amount reach USD500 |
| Quality Control |
HNMR,CNMR,LCMS,HPLC,IR,etc. |
| Price & Availability |
In Stock. Price Negotiated. |
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