| AMG-073 (Cinacalcet hydrochloride) |
| αR-methyl-N-[3-[3-(trifluoromethyl)phenyl]propyl]-1-naphthalenemethanamine,monohydrochloride |
| (CAS 364782-34-3) |
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| Description： |
Cinacalcet is a calcimimetic that allosterically activates the calcium-sensing receptor (CaSR; pEC50 = 7.3 in HEK 293T cells expressing CaSR).In the presence of calcium ions,it can inhibit parathyroid hormone secretion by activating CaSR in parathyroid glands.Cinacalcet has been used clinically to treat secondary hyperparathyroidism due to end-stage renal disease or hypercalcemia in patients with parathyroid carcinoma.
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| Product No. |
KT00069 |
| Product Name |
AMG-073 (Cinacalcet hydrochloride) |
| Synonyms |
Mimpara,AMG 073,Sensipar,KRN 1493 |
| Formal Name |
αR-methyl-N-[3-[3-(trifluoromethyl)phenyl]propyl]-1-naphthalenemethanamine,monohydrochloride |
| CAS Number |
364782-34-3 |
| Molecular Formula |
C22H22F3N•HCl |
| Formula Weight |
393.9 |
| Formulation |
A crystalline solid |
| Purity |
98%min |
| Stability |
2 years |
| Storage |
-20°C |
| Shipping |
USD45 for Europe and USA. No shipping charge once amount reach USD500 |
| Quality Control |
HNMR,CNMR,LCMS,HPLC,IR,etc. |
| Price & Availability |
In Stock. Price Negotiated. |
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| Related Products： |
Calcium-Sensing Receptor Antagonists I
Cinacalcet
NPS-2143
NPS-2143 hydrochloride
Strontium Ranelate
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