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RWJ 67657 
4-(4-Fluorophenyl)-2-(4-hydroxy-1-butynyl)-1-(3-phenylpropyl)-5-(4-pyridyl)imidazole
(CAS 215303-72-3)
Description:

RWJ 67657 is a p38/JNK kinase inhibitor with anti-inflammatory properties.

Studies show that RWJ 67657 inhibits tyrosine kinases p56 lck and c-src, and blocks TNF-α production. RWJ 67657 has been shown to block HIV replication in T-cell and monocyte cells. Additional studies report a decrease of chemokine production, E-selectin, IL-8, and COX-2 expression in the presence of RWJ 67657.

 

Product No. KT00784 
Product Name RWJ 67657 
Synonyms JNJ 3026582
Formal Name 4-(4-Fluorophenyl)-2-(4-hydroxy-1-butynyl)-1-(3-phenylpropyl)-5-(4-pyridyl)imidazole
CAS Number 215303-72-3
Molecular Formula C27H24FN3O
Formula Weight 425.51
Formulation A crystalline solid
Purity 98%min
Stability 2 years
Storage -20°C
Shipping USD45 for Europe and USA. No shipping charge once amount reach USD500
Quality Control HNMR,CNMR,LCMS,HPLC,IR,etc.
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