| RWJ 67657 |
| 4-(4-Fluorophenyl)-2-(4-hydroxy-1-butynyl)-1-(3-phenylpropyl)-5-(4-pyridyl)imidazole |
| (CAS 215303-72-3) |
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| Description: |
RWJ 67657 is a p38/JNK kinase inhibitor with anti-inflammatory properties.
Studies show that RWJ 67657 inhibits tyrosine kinases p56 lck and c-src, and blocks TNF-α production. RWJ 67657 has been shown to block HIV replication in T-cell and monocyte cells. Additional studies report a decrease of chemokine production, E-selectin, IL-8, and COX-2 expression in the presence of RWJ 67657.
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| Product No. |
KT00784 |
| Product Name |
RWJ 67657 |
| Synonyms |
JNJ 3026582 |
| Formal Name |
4-(4-Fluorophenyl)-2-(4-hydroxy-1-butynyl)-1-(3-phenylpropyl)-5-(4-pyridyl)imidazole |
| CAS Number |
215303-72-3 |
| Molecular Formula |
C27H24FN3O |
| Formula Weight |
425.51 |
| Formulation |
A crystalline solid |
| Purity |
98%min |
| Stability |
2 years |
| Storage |
-20°C |
| Shipping |
USD45 for Europe and USA. No shipping charge once amount reach USD500 |
| Quality Control |
HNMR,CNMR,LCMS,HPLC,IR,etc. |
| Price & Availability |
In Stock. Price Negotiated. |
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