| Combrestatin A4 |
| 2-methoxy-5-[(1Z)-2-(3,4,5-trimethoxyphenyl)ethenyl]-phenol |
| (CAS 117048-59-6) |
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| Description： |
Combrestatin A4 (CA4) is a potent inhibitor of tubulin polymerization and displays strong inhibitory activity on tumor cell growth. Combrestatin A4 was shown to inhibit tumor growth in several cell lines including IMR32 (neuroblastoma), Hs746T (gastric carcinoma), CFPAC-1 (pancreatic carcinoma), and MCF-7 (breast cancer) with IC50 values of 2.16, 5.20, 3.46, and 18.47 nM, respectively.CA4 inhibits tubulin polymerization with an IC50 value of 2.2 µM.
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| Product No. |
KT20052 |
| Product Name |
Combrestatin A4 |
| Synonyms |
CA4; Combretastatin A4; CRC 87-09 |
| Formal Name |
2-methoxy-5-[(1Z)-2-(3,4,5-trimethoxyphenyl)ethenyl]-phenol |
| CAS Number |
117048-59-6 |
| Molecular Formula |
C18H20O5 |
| Formula Weight |
316.4 |
| Formulation |
A crystalline solid |
| Purity |
98%min |
| Stability |
2 years |
| Storage |
-20°C |
| Shipping |
USD45 for Europe and USA. No shipping charge once amount reach USD500 |
| Quality Control |
HNMR,CNMR,LCMS,HPLC,IR,etc. |
| Price & Availability |
In Stock. Price Negotiated. |
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