| KN-62 |
| 4-[(2S)-2-[(5-isoquinolinylsulfonyl)methylamino]-3-oxo-3-(4-phenyl-1-piperazinyl)propyl]phenyl ester, 5-isoquinolinesulfonic acid |
| (CAS 127191-97-3) |
 |
| Description： |
KN-62 is a selective, cell permeable inhibitor of Ca2+/calmodulin-dependent kinase type II (CaMKII; IC50 = 900 nM). It does not affect the activity of several other kinases when tested at 10 µM. KN-62 also acts as a non-competitive antagonist of the purinergic receptor P2RX7 (IC50 = 15 nM).
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| Product No. |
KT00480 |
| Product Name |
KN-62 |
| Synonyms |
|
| Formal Name |
4-[(2S)-2-[(5-isoquinolinylsulfonyl)methylamino]-3-oxo-3-(4-phenyl-1-piperazinyl)propyl]phenyl ester, 5-isoquinolinesulfonic acid |
| CAS Number |
127191-97-3 |
| Molecular Formula |
C38H35N5O6S2 |
| Formula Weight |
721.9 |
| Formulation |
A crystalline solid |
| Purity |
98%min |
| Stability |
2 years |
| Storage |
-20°C |
| Shipping |
USD45 for Europe and USA. No shipping charge once amount reach USD500 |
| Quality Control |
HNMR,CNMR,LCMS,HPLC,IR,etc. |
| Price & Availability |
In Stock. Price Negotiated. |
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| Related Products： |
A 438079
A 839977
A-317491
A-740003
CaMKII-IN-1
KN-92
KN-93
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