| AMG 073 |
| (R)-N-[1-(1-naphthyl)ethyl]-3-[3-(trifluoromethyl)phenyl]propan-1-amine |
| (CAS 226256-56-0) |
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| Description： |
Cinacalcet (INN) is a drug that acts as a calcimimetic (i.e. it mimics the action of calcium on tissues) by allosteric activation of the calcium-sensing receptor that is expressed in various human organ tissues.It is sold by Amgen under the trade name Sensipar in North America and Australia and as Mimpara in Europe.Cinacalcet is used to treat secondary hyperparathyroidism (elevated parathyroid hormone levels),a consequence of end-stage renal disease.[1] Cinacalcet is also indicated for the treatment of hypercalcemia in patients with parathyroid carcinoma.[2] Cinacalcet was FDA approved in March 2004.[3]
Clinical trials conducted in the United States by Amgen to determine whether the drug is safe for children were halted by the FDA in February 2013 following the death of a 14-year-old patient.[4]
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| Product No. |
KT00068 |
| Product Name |
AMG 073 |
| Synonyms |
Cinacalcet |
| Formal Name |
(R)-N-[1-(1-naphthyl)ethyl]-3-[3-(trifluoromethyl)phenyl]propan-1-amine |
| CAS Number |
226256-56-0 |
| Molecular Formula |
C22H22F3N |
| Formula Weight |
357.41 |
| Formulation |
A crystalline solid |
| Purity |
98%min |
| Stability |
2 years |
| Storage |
-20°C |
| Shipping |
USD45 for Europe and USA. No shipping charge once amount reach USD500 |
| Quality Control |
HNMR,CNMR,LCMS,HPLC,IR,etc. |
| Price & Availability |
In Stock. Price Negotiated. |
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| Related Products： |
NPS-2143
NPS-2143 hydrochloride
Cinacalcet hydrochloride
Calcium-Sensing Receptor Antagonists I
Strontium Ranelate
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